Branched-chain .ALPHA.-ketoacids and related acids in thiamin-deprived rats.
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چکیده
منابع مشابه
Branched-chain amino acids alter neurobehavioral function in rats.
Recently, we have described a strong association of branched-chain amino acids (BCAA) and aromatic amino acids (AAA) with obesity and insulin resistance. In the current study, we have investigated the potential impact of BCAA on behavioral functions. We demonstrate that supplementation of either a high-sucrose or a high-fat diet with BCAA induces anxiety-like behavior in rats compared with cont...
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The decarboxylase/dehydrogenase (E1b) component of the 4-megadalton human branched-chain alpha-keto acid dehydrogenase (BCKD) metabolic machine is a thiamin diphosphate (ThDP)-dependent enzyme with a heterotetrameric cofactor-binding fold. The E1b component catalyzes the decarboxylation of alpha-keto acids and the subsequent reductive acylation of the lipoic acid-bearing domain (LBD) from the 2...
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ژورنال
عنوان ژورنال: Journal of Nutritional Science and Vitaminology
سال: 1989
ISSN: 0301-4800,1881-7742
DOI: 10.3177/jnsv.35.163